A.L. Bortree was Professor Emeritus and former head of the Department of Veterinary & Biomedical Sciences at the Pennsylvania State University. The series is sponsored by the Department of Veterinary & Biomedical Sciences and the graduate program in Pathobiology (including faculty affiliated with Biochemistry and Molecular Biology, Chemistry, Nutrition and Biology).

If you would like to meet with a presenter or have any questions on upcoming lecturers, contact (814) 863-5786 or via e-mail at Pathobiology@psu.edu.

Spring 2008

• Kenneth Thummel, Ph D, University of Washington. TBA.

• Dr. Adolfo Garcia-Sastre, Ph D, Mount Sinai School of Medicine. TBA.

• Dr. Charles Serhan, Ph D, Harvard Medical School. TBA.

• Terence S. Dermody, M.D., Vanderbilt University School of Medicine . TBA.

• Bharat B. Aggarwal, M.D., Anderson Cancer Center. TBA.

Fall 2007

• Anjano Rao , Ph D, TBA. TBA.

• Maurreen Murphy, Ph D, Fox Chase Cancer Center. TBA.

• Dr. Danni Welch, Ph D, TBA. TBA.

• Dr. Jeff Idle, Ph D, University of Prague. TBA.

• Dr. Devin G. Peterson, Ph D, Food Science, PSU . TBA .

• Robert Lamb, Ph D, Howard Hughtes Medical Institute, IL . TBA.

• Luke O’Neall, Ph D, Trinity College, Dublin Ireland . TBA.

• Rebecca Morris, Ph D, TBA. TBA.

• Tom Rushmore, Ph D, TBA. TBA.

• Weston Porter , MD, Texas A&M University. TBA.

• Sankar Gosh, Ph D, Immunobiology & Molecular Biophysics & Biochemistry, Yale University School of Medicine. TBA.

• Vadim N. Gladyshev, Ph D, Biochemistry, University of Nebraska. TBA.

• Melinda Beck, Ph D, Department of Nutrition, University of North Carolina at Chapel Hill. TBA.

• Susan Mallery, Ph D, Ohio State University. TBA.

• Mervin Yoder Jr., MD, Pediatrics, Indiana University School of Medicine. TBA.

• Ashis Basu, Ph D, University of Conneticut. TBA.

• Barry Paw, MD, Ph D, Hematology/Oncology, Bringham & Women's Hospital, Boston, Ma. TBA.

• Celeste Simon, Ph D, Abramson Family Center Research Institute, Philadelphia PA. TBA.

• Richard Lang, Ph D, Cincinatti Children's Hospital Medical Center. TBA.

• Jong Yun, Ph D, Pharmacology - Hershey Medical Center, Hershey PA. TBA.

• David Scadden, MD, Professor of Medicine - Harvard University. TBA.

Spring 2007

• Volker Vogt, Ph D, Professor of Molecular Biology - Cornell University. TBA.

• Jeffery Bergelson, Ph D, Associate Professor of Pediatrics. TBA.

• Manuel Llinās, Ph D, Assistant Professor - Department of Molecular Biology - Lewis-Sigler Institute - Princeton University. TBA.

• J. Glenn Songer, Ph D, Department of Veterinary Science and Microbiology - University of Arizona. The Extraordinary Imperialism of the Clostridia.

Fall 2006

• Alan Diamond, Ph D, Professor and Head, Department of Human Nutrition, University of Illinois at Chicago, Chicago, IL . Chemoprevention with selenium: If so, how?.

• Jianke Zhang, Ph D, Assistant Professor of Microbiology and Immunology, Thomas Jefferson Univ, Philadelphia, PA. Regulation of Proliferation and Apoptosis by the DISC (death-inducing signaling complex) protein.

• Xuming Zhang, DVM, Ph D, Professor of Molecular Virology, University of Arkansas for Medical Sciences, Little Rock, AR. The Yin and Yang of Coronavirus Infection in CNS Cells.

• Janet MacInnes, Ph D, Associate Professor of Bacteriology, Department of Pathobiology, Ontario Veterinary College, Guelph, Canada. When "Good" Bugs go "Bad": Molecular Pathogenesis Studies of Actinobacillus suis.

• Warner Greene, MD, Ph D, Director, Gladstone Institute of Virology and Immunology, Univ of CA, San Francisco. Deciphering the Biology of APOBEC3G: More Than an Anti-HIV Factor.

• Troy Ott, Ph D, Associate Professor of Reproductive Biology, Dairy and Animal Science, Penn State. Maternal immune responses to pregnancy recognition signaling in ruminants.

• Phillip Scott, Ph D, Associate Dean for Research, School of Veterinary Medicine, University of Pennsylvania. Memory T cells and chronic disease: How memory develops and is maintained during Leishmania major infections.

• David Wiest, Ph D, Division of Basic Sciences, Fox Chase Cancer Ctr, Philadelphia, PA. Regulation of T lineage commitment in the thymus.

• P. Patrick Cleary, Ph D, Department of Microbiology, U of MN Med School . Group A streptococci,TGF beta 1 induced integrin upregulation and infection of tonsils.

• Laurel L. Lenz, Jr., Ph D, Assistant Professor, Integrated Department of Immunology, National Jewish Medical and Research Center, Denver, CO. Listeria monocytogenes autolysins and bacterial subversion of innate immunity.

• Dr. Cornelis Elferink, Ph D, University of Texas Medical Branch. Ah Receptor-Regulated Mechanisms in Hepatocyte Cell Cycle Control.

Spring 2006

• John Karn, Ph D, Case Western (AH). TBD.

• John Schultz, Ph D, St. Jude Children's Research Hospital (CO). TBD.

• Russell Prough, PhD, University of Louisville, (GP). DHEA: Ligand-dependent & independent activation of PPAR alpha .

• Jeff Miller, MD, Molecular Biology & Genetics Section, NIDDK, MD (RP). Erythroid Biology in a Post-Genomic World.

• Jose Manuat, Ph D, University of Connecticut. Peroxisome Proliferation and Resistance to Drug-Induced Liver Disease.

• Leslie Parent, MD, Professor, Medicine and Microbiology and Immunology, Division of Infectious Diseases, Hershey Medical Center . Nuclear trafficking events in retrovirus replication.

• Rachel Tyndale, Ph D, University of Toronto (CO). Drug-inducible cytochromes P450 in the brain: Potential roles in drug efficacy and toxicity.

• Rajesh Agarwal, Ph D, University of Colorado- School of Pharmacy (JP). Molecular Mechanism of Skin Cancer Chemoprevention by Silibinin.

• Jill P Smith, MD, Professor of Medicine, GI and Hepatology, Hershey Medical School. Gastrointestinal Research: Bench to Bedside.

• JoAnne Flynn, Ph D, Department of Molecular Genetics and Biochemistry, University of Pittsburgh School of Medicine. Dynamic immune response to tuberculosis in the lungs.

• Erik Hewlett, M D, Department of Internal Medicine & Pharmacology, University of Virginia Health System. Bacterial adenylalte cyclase toxins: more than just making cyclic AMP!.

• Lishan Su, Ph D, Departments of Microbiology and Immunology, School of Medicine, University of North Carolina . HIV-1 replication in Treg cells: tipping the immune balance.

• Michael Flanagan, MD, Hershey Medical Center. Pertussis: The Re-Emergence of an Old Disease.

• Mary Ann McDowell, Ph D, Notre Dame (MC). Vector, Pathogen, Host, The Infectious Trinity.

• Hyeryun Choe, Ph D, Children's Hospital, Boston MA (AH). Viral Entry: from HIV-1 to SARS-CoV.

• Kelly McNagny, Ph D, University of British Columbia (RP). Teflon and glue/life and death: The CD34 family of sialomucins.

Fall 2005

• Saghi Ghaffari, MD, Ph D, Assistant Professor, Department of Gene and Cell Medicine, Mount Siani School of Medicine, New York, NY. Erythropoietin Receptor Signaling and the Transcriptional Program of Red Cell Maturation.

• Charles Vinson, Ph D, NIH, Bethesda, Maryland. AP-1 Regulates Epidermal Cell Identity.

• Edward Medof, MD, PhD, Professor, Department of Pathology, Case Western Reserve University. New Insights Into T Cell Activation: Relevance to Autoimmunity and Immune Privilege.

• Linheng Li, Ph D, Assistant Investigator, Stowers Institute for Medical Research, Kansas City, MO. Hematopoietic Stem Cells and Niche Regulation.

• Jeffrey Watts, Ph D, Senior Research Scientist, Veterinary Medicine Research and Development, Pfizer Animal Health, Kalamazoo, MI. Rational Use of Antibiotics in Veterinary Medicine: The Role of Antimicrobial Susceptibility Testing.

• Frits Mooi, Ph D, Laboratory for Vaccine Preventable Diseases, Netherlands. The re-emergence of pertussis: Waning immunity or adaptation?.

• Steve Rubin, Ph D, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, MD. Genetic Markers of Mumps Virus Neuroattenuation.

• Richard Moyer, Ph D, Professor, Department of Molecular Genetics and Microbiology, University of Florida College of Medicine. Poxvirus serpins: A unique class of host response modifier genes - From bench to bedside.

• P. Reddanna, Ph D, Professor, Department of Animal Sciences, School of Life Sciences, University of Hyderabad, India. Development of potential natural and synthetic drug candidates against chronic myeloid leukemia.

• Shantu Amin, Ph D, Hershey Medical Center, Penn State University. Carcinogenesis and Chemoprevention.

• Tatiana Oberyszyn, Ph D, Ohio State University. Ultraviolet induced skin cancer. Is there hope?.

• Rajesh Agarwal, Ph D, University of Colorado School of Pharmacy. Molecular Mechanism of Skin Cancer Chemoprevention by Silibinin.

• Eddie Holmes, Ph D, Professor, Department of Biology, Penn State University. Life at the Edge: The Evolutionary Biology of RNA Viruses.

Spring 2005

• Nancy Speck, Ph D, Professor Biochemistry, Associate Director of Basic Science, Vail Dartmouth Medical School, Hanover, NH. Runx1-CBF-beta in hematopoiesis and leukemia.

• Steve Dewhurst, Ph D, Professor, Microbiology & Immunology, University of Rochester Medical Center. Recent studies on human herpesvirus-6: Functional anlaysis of the significance of a virally encoded 7-transmembrane receptor..

• Michael Oglesbee, DVM, Ph D, Professor, Department of Veterinary Biosciences, The Ohio State University. Morbillivirus-Heat Shock Protein Interaction - a Double Edged Sword.

• Kendall Wallace, Ph D, Professor, Department of Biochemistry & Molecular Biology, University of Minnesota Medical School. Adriamycin-induced Mitochondrial Cardiomyopathy - Molecular Basis for Persistent Metabolic Adaptations.

• Mark Boothby, MD, Ph D, Associate Professor, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, TN. Fate(ful) Decisions of CD4 T Cells: Molecular Regulation of Effector Responses in the Helper Lineage of Lymphocytes.

• Stefanie Vogel, Ph D, Professor, Microbiology & Immunology, Department of Medicine, University of Maryland. Mutations in TLR4 Signaling and Susceptibility to Infection.

• Douglas Lyles, Ph D, Professor, Chairman of Biochemistry, Wake Forest University School of Medicine, Winston-Salem, NC. Regulation of cell death and host antiviral responses by vesticular stomatitis virus matrix protein.

• Sue A. Moyer, Ph D, Professor, Molecular Genetics & Microbiology, University of Florida. The Roles of the L Polymerase Protein of Negative Strand RNA Viruses in RNA Synthesis and Cap Methylation.

• William McAllister, Ph D, Professor and Chair, Morse Institute of Molecular Genetics, Department of Microbiology and Immunology, SUNY Downstate Medical Center. Biochemical and genetic characterization of conformational changes that occur in T7 RNAP during the transition from initiation to elongation.

• Ivan Rusyn, Ph D, Assistant Professor, Department of Environmental Sciences & Engineering, School of Public Health, University of North Carolina. The elusive role of oxidant-induced DNA damage in the mechanisms of non-genotoxic liver carcinogenesis: Did not we figure it out a decade ago?.

• Jianming Hu, MD, Ph D, Associate Professor, Department of Microbiology and Immunology, Penn State College of Medicine, Hershey, PA. Virus-Cell Interactions in Hepatitis B Virus Assembly and Replication.